Rebecca Steiner, Ph.D.
About Rebecca Steiner, Ph.D.
Dr. Steiner earned a Bachelor of Science from The University of Mount Union in Ohio. She then went to The Ohio State University to complete a Ph.D. in Biochemistry. She completed a research fellowship at the Lineberger Cancer Center at The University of North Carolina at Chapel Hill. Currently, she is an Assistant Professor of Biochemistry and Genetics for LECOM in Bradenton, Florida in the College of Medicine.
Research question:
How does disturbance of translational quality control impact Gram-positive (Bacillus subtills) and Gram-negative (Escherichia coli) bacteria differently?
Background and Preliminary results:
The amino acyl tRNA synthetase is the enzyme responsible for attaching the correct amino acid to a tRNA to be used in translation. Without internal proofreading mechanisms, errors can occur during protein synthesis.
Mutation of the editing domain in E. coli induces growth defect, among other phenotypes, including antibiotic sensitivities. However, the same mutation in B. subtills does not induce a growth deficiency.
The Latest Publications from Dr. Rebecca Steiner
2019 Canals, R., Chaudhuri, R.R., Steiner, R.E., Owen, S.V., Quinones-Olvera, N., Gordon, M.A., Baym, M., Ibba, M. and Hinton, J. C. D. “ The fitness landscape of the African Salmonella Typhimurium SY313 strain D23580 reveals unique properties of the pBT1 plasmid,” PLOS Pathogen, 2019 15(9): e1007948.
