The use of natural products in medicine provides a natural means to treat disease. My research aims to isolate and identify bioactive molecules from wine grapes grown in the Lake Erie Wine Region. Using pomace (the skins, stems, and pulp of grape which remain after pressing) from local wineries the project employs chemical extractions and chromatographic techniques to isolate compounds produced by nature. Once isolated, these compounds will be examined, in collaboration with other LECOM research labs, for bioactivity in antimicrobial assays. The techniques employed have applications across natural products and could be used to examine other natural sources of bioactive compounds.