Best Evidence Analyses and Commentary

Updated Recommendations for Tdap Vaccination in Pregnancy
Edward McLean, PharmD Candidate; Marcus Campbell, PharmD
June 21, 2013

According to the data from the Center for Disease Control (CDC) on communicable diseases, the incidence of pertussis cases has been increasing over the past several years, most notably among the infant population.1 In order to combat this rising trend, The Advisory Committee on Immunization practices (ACIP) revised and produced new guidelines for Tetanus, Diphtheria, and Pertussis (Tdap) vaccinations in women who are pregnant. ACIP recommendations are based on scientific data which supports the contention that maternal antibodies produced after Tdap administration will protect infants post-partum until the time they are able to receive the proper immunizations.2


1. CDC. Notifiable diseases and mortality tables. MMWR 2012;61:ND 719-32

2. Updated Recommendations for Use of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine (Tdap) in Pregnant Women — Advisory Committee on Immunization Practices (ACIP), 2012. MMWR 2013; 62:131-135

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